Isabelle_DOF/examples/cytology/Cytology.thy

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theory Cytology
imports "Isabelle_DOF.scholarly_paper"
begin
text\<open>A small example ontology for demonstration purposes.
The presentation follows closely: \<^url>\<open>https://www.youtube.com/watch?v=URUJD5NEXC8\<close>.\<close>
datatype protein = filaments | motor_proteins | rna | dna |nucleolus
type_synonym desc = "string"
onto_class organelles = description :: desc
find_theorems (60) name:"organelles"
term "Cytology.organelles.make"
onto_class ribosomes = organelles + description :: desc
onto_class mytochondria = organelles + description :: desc
onto_class golgi_apparatus = organelles + description :: desc
onto_class lysosome = organelles + description :: desc
text\<open>the control center of the cell:\<close>
onto_class nucleus = organelles +
description :: desc
components :: "protein list" <= "[nucleolus]"
(* Not so nice construction to mimick inheritance on types useds in attribute positions. *)
datatype organelles' = upcast\<^sub>r\<^sub>i\<^sub>b\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e\<^sub>s (get_ribosomes:ribosomes)
| upcast\<^sub>m\<^sub>y\<^sub>t\<^sub>o\<^sub>c\<^sub>h\<^sub>o\<^sub>n\<^sub>d\<^sub>r\<^sub>i\<^sub>a (get_mytochondria:mytochondria)
| upcast\<^sub>g\<^sub>o\<^sub>l\<^sub>g\<^sub>i\<^sub>_\<^sub>a\<^sub>p\<^sub>p\<^sub>a\<^sub>r\<^sub>a\<^sub>t\<^sub>u\<^sub>s (get_golgi_apparatus: golgi_apparatus)
| upcast\<^sub>l\<^sub>y\<^sub>s\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e (get_lysosome : lysosome)
| upcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s (get_nucleus : nucleus)
fun is\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s where "is\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s (upcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s X) = True" | "is\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s ( _) = False"
(* ... *)
fun downcast\<^sub>r\<^sub>i\<^sub>b\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e\<^sub>s
where "downcast\<^sub>r\<^sub>i\<^sub>b\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e\<^sub>s (upcast\<^sub>r\<^sub>i\<^sub>b\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e\<^sub>s X) = X" | "downcast\<^sub>r\<^sub>i\<^sub>b\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e\<^sub>s _ = undefined"
fun downcast\<^sub>m\<^sub>y\<^sub>t\<^sub>o\<^sub>c\<^sub>h\<^sub>o\<^sub>n\<^sub>d\<^sub>r\<^sub>i\<^sub>a
where "downcast\<^sub>m\<^sub>y\<^sub>t\<^sub>o\<^sub>c\<^sub>h\<^sub>o\<^sub>n\<^sub>d\<^sub>r\<^sub>i\<^sub>a (upcast\<^sub>m\<^sub>y\<^sub>t\<^sub>o\<^sub>c\<^sub>h\<^sub>o\<^sub>n\<^sub>d\<^sub>r\<^sub>i\<^sub>a X) = X" | "downcast\<^sub>m\<^sub>y\<^sub>t\<^sub>o\<^sub>c\<^sub>h\<^sub>o\<^sub>n\<^sub>d\<^sub>r\<^sub>i\<^sub>a _ = undefined"
fun downcast\<^sub>g\<^sub>o\<^sub>l\<^sub>g\<^sub>i\<^sub>_\<^sub>a\<^sub>p\<^sub>p\<^sub>a\<^sub>r\<^sub>a\<^sub>t\<^sub>u\<^sub>s
where "downcast\<^sub>g\<^sub>o\<^sub>l\<^sub>g\<^sub>i\<^sub>_\<^sub>a\<^sub>p\<^sub>p\<^sub>a\<^sub>r\<^sub>a\<^sub>t\<^sub>u\<^sub>s (upcast\<^sub>g\<^sub>o\<^sub>l\<^sub>g\<^sub>i\<^sub>_\<^sub>a\<^sub>p\<^sub>p\<^sub>a\<^sub>r\<^sub>a\<^sub>t\<^sub>u\<^sub>s X) = X" | "downcast\<^sub>g\<^sub>o\<^sub>l\<^sub>g\<^sub>i\<^sub>_\<^sub>a\<^sub>p\<^sub>p\<^sub>a\<^sub>r\<^sub>a\<^sub>t\<^sub>u\<^sub>s _ = undefined"
fun downcast\<^sub>l\<^sub>y\<^sub>s\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e
where "downcast\<^sub>l\<^sub>y\<^sub>s\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e (upcast\<^sub>l\<^sub>y\<^sub>s\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e X) = X" | "downcast\<^sub>l\<^sub>y\<^sub>s\<^sub>o\<^sub>s\<^sub>o\<^sub>m\<^sub>e _ = undefined"
fun downcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s
where "downcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s (upcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s X) = X" | "downcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s _ = undefined"
onto_class cell =
name :: string
membrane :: desc <= "\<open>The outer boundary of the cell\<close>"
cytoplasm :: desc <= "\<open>The liquid in the cell\<close>"
cytoskeleton :: desc <= "\<open>includes the thread-like microfilaments\<close>"
genetic_material :: "protein list" <= "[rna, dna]"
text\<open>Cells are devided into two categories: \<^emph>\<open>procaryotic\<close> cells (unicellular organisms some
bacteria) without a substructuring in organelles and \<^emph>\<open>eucaryotic\<close> cells, as occurring in
pluricellular organisms\<close>
onto_class procaryotic_cells = cell +
name :: string
onto_class eucaryotic_cells = cell +
organelles :: "organelles' list"
invariant has_nucleus :: "\<lambda>\<sigma>::eucaryotic_cells. \<exists> org \<in> set (organelles \<sigma>). is\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s org"
\<comment>\<open>Cells must have at least one nucleus. However, this should be executable.\<close>
find_theorems (70)name:"eucaryotic_cells"
find_theorems name:has_nucleus
value "is\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s (mk\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s X)"
term \<open>eucaryotic_cells.organelles\<close>
value \<open>(eucaryotic_cells.organelles(eucaryotic_cells.make X Y Z Z Z [] 3 []))\<close>
value \<open>has_nucleus_inv(eucaryotic_cells.make X Y Z Z Z [] 3 [])\<close>
value \<open>has_nucleus_inv(eucaryotic_cells.make X Y Z Z Z [] 3
[upcast\<^sub>n\<^sub>u\<^sub>c\<^sub>l\<^sub>e\<^sub>u\<^sub>s (nucleus.make a b c d [])])\<close>
end